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statin and inflamation

Effect of Atorvastatin versus Rosuvastatin on level of inflammatory markers and low density lipoprotein-cholesterol (LDL) in Patients with acute coronary syndrome: double blind randomize control trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190903044682N1
Enrollment
84
Registered
2019-12-26
Start date
2019-09-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Levels of inflammatory markers. ????? ?????? ?? ?????? ????

Interventions

Intervention 1: Intervention group: atrovastetin is a drug manufactured by Abidi Pharmaceutical Company at a dose of 80 mg once daily after dinner for 60 days. Intervention 2: Intervention group: Rosv

Sponsors

Neyshabour University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Acute coronary syndrome based on clinical signs and ECG and serum markers

Exclusion criteria

Exclusion criteria: renal failure Liver failure Immunosuppressants, corticosteroids or potent inhibitors of cytochrome P450 3A4, pentoxifylline, silostazole, glucosamine, berberine barberry extract Having underlying inflammatory or infectious diseases Left Schiff's Leukostosis TG>400 CHF with NYHA III or IV Having a history of diseases that cause malabsorption syndromes Uncontrolled blood pressure Evidence of endocrine or metabolic disease affecting lipid profile

Design outcomes

Primary

MeasureTime frame
Blood levels of inflammatory markers. Timepoint: Before starting the study and 60 days later beginning. Method of measurement: Laboratory measurement by ELISA.

Secondary

MeasureTime frame
Lipid profile. Timepoint: Before the intervention and at the end of the intervention. Method of measurement: Laboratory measurement with Pars test kit with Autoanalyzer bt 3000.;Blood levels of inflammatory markers. Timepoint: Before the intervention and at the end of the intervention. Method of measurement: Laboratory tests.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedeh Samaneh Tabaee

Neyshabour University of Medical Sciences

tabaees@nums.ac.ir0985142255524

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026