Condition 1: Ventricular tachycardia. Condition 2: Ventricular tachycardia.
Conditions
Interventions
Intervention 1: Intervention group 1: Lidocaine plus Magnesium Sulfate
Lidocaine 2 mg / kg plus Magnesium Sulfate 30 mg/kg and normal saline will be administered up to a total volume of 25 ml using infusion pump 5 minutes before the cross-clamp is opened. Intervention 2:
Sponsors
Rajaie Cardiovascular Medical and Research Center
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patient consent to participate in the study 18 years of age or older No previous cardiac surgery No contraindication or severe allergy to amiodarone, Lidocaine and Magnesium Sulfate Normal serum levels of liver enzymes Serum creatinine levels are less than 2 mg / dL.
Exclusion criteria
Exclusion criteria: Transient cerebral ischemia or stroke Uncontrolled diabetes mellitus during study Carotid artery stenosis over 50% Uncontrolled hypertension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of ventricular tachyarrhythmias. Timepoint: During the bypass and 5 minutes before the cross-clamp opening. Method of measurement: Electrocardiograph. | — |
Secondary
| Measure | Time frame |
|---|---|
| Ejection Fraction. Timepoint: 24 hours after intervention. Method of measurement: Echocardiography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFateme Hesari
Shahid Rajaee Cardiovascular Medical and Research Center
Outcome results
None listed