The effect of vaginal misoprostol and isosorbide mononitrate on under 20 week miscarriages

Efficacy of vaginal Misoprostol, Isosorbide Mononitrate and giving time without medication for preoperative cervical ripening in under 20 weeks abortion

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190901044658N1

Enrollment

120

Registered

2019-12-07

Start date

2019-06-22

Completion date

Unknown

Last updated

2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervix Preparation for Abortion. Missed abortion

Interventions

Intervention 1: Intervention group 1: The first group will be given vaginal misoprostol, 200 µg every 6 hours up to 13 weeks of gestational age and 200 µg every 6-12 hours from 14 to 20 weeks of gesta

Eligibility

Sex/Gender

Female

Age

15 Years to 40 Years

Inclusion criteria

Inclusion criteria: Gestational age under 20 weeks candidate for abortion due to proved fetal death confirmed by sonography severe abnormality in which the fetus is not viable

Exclusion criteria

Exclusion criteria: Certain underlying disease such as cancer

Design outcomes

Primary

Measure	Time frame
The time of the cervix preparation for abortion. Timepoint: The patient will be examined regularly every 6 hours, and if the fetus is not discharged, the drug will be repeated after 6 to 12 hours. Method of measurement: It will be a clinical and cervical examination by a resident resident.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahla Farzipour

Ardabil University of Medical Sciences

meisamfooladi@gmail.com+98 45 3323 0739

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026