Gastroesophageal reflux disease (GERD). Gastro-esophageal reflux disease
Conditions
Interventions
Intervention 1: Intervention group: Ordinary yogurt. Intervention 2: Intervention group: Probiotics yogurt. Intervention 3: Control group: Omeprazole.
Sponsors
Bojnourd University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The patient be literate or someone helps him/her in filling the questionnaires Patients should be geographically accessible
Exclusion criteria
Exclusion criteria: Age less than 18 years Allergy to dairy products Pregnancy History of gastrointestinal malignancy History of gastric and esophageal surgery and small bowel bypass Liver and kidney and heart dysfunction Concomitant use of NSAIDs and aspirin for up to one week before the study Anticancer or antibiotic use during 4 weeks before referral and participation in this study No anti-acid, hydrogen pump inhibitors, H2 receptor inhibitors in two groups of yogurt recipients during the study Receiving bisphosphenate, cortisone, potassium chloride or iron tablets concurrently in the study Patient's compliance be less than 80% (self-reported by patient)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effect on the GERD severity. Timepoint: Baseline, one month and tow months later. Method of measurement: The Gastroesophageal Reflux Disease-Health Related Quality of Life instrument (related to typical symptoms).;Effect on the severity of GERD atypical symptoms. Timepoint: Baseline, one month and tow months late. Method of measurement: Reflux Symptom Index and Disease Specific Quality of Life Index questionnaires (related to atypical symptoms). | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of quality of life. Timepoint: At baseline, one month and tow months later. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Javad Pournaghi
Bojnourd University of Medical Sciences
Outcome results
None listed