Effect of 8 weeks of Pilates exercise and vitamin D on Tumor necrosis factor-a and interleukin-10 levels in overweight men

Investigating the changes of Tumor necrosis factor-a and Interleukin-10 after 8 weeks of regular Pilates exercise and vitamin D intake in overweight men

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190831044650N2

Enrollment

Registered

2020-03-18

Start date

2019-12-31

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity and overweight. Obesity due to excess calories

Interventions

Intervention 1: Intervention group 1: Exercise group will perform 8 weeks of Pilates exercises with 50-55% of heart rate reserve, one set and 10 repetitions in the first week and 65-70% reserve heart

Eligibility

Sex/Gender

Male

Age

40 Years to 55 Years

Inclusion criteria

Inclusion criteria: Being overweight Not having regular exercise for the past six months Ability to perform exercise training Not having cardiovascular disease Not having hypertension

Exclusion criteria

Exclusion criteria: Use of specific drugs Use of supplement smoking

Design outcomes

Primary

Measure	Time frame
Tumor necrosis factor-a. Timepoint: Before and after interventions. Method of measurement: Using the ELISA method.;25- hydroxy vitamin D. Timepoint: Before and after interventions. Method of measurement: Using the ELISA method.;Interleukin-10. Timepoint: Before and after interventions. Method of measurement: Using the ELISA method.;Thyroid Stimulating Hormone. Timepoint: Before and after interventions. Method of measurement: immunochemiluminescence assay.;C-Reactive Protein. Timepoint: Before and after interventions. Method of measurement: Using the ELISA method.;Insulin. Timepoint: Before and after interventions. Method of measurement: Using the ELISA method.;Insulin resistance. Timepoint: Before and after interventions. Method of measurement: Using the homeostasis model(HOMA-IR).	—

Measure

Time frame

Tumor necrosis factor-a. Timepoint: Before and after interventions. Method of measurement: Using the ELISA method.;25- hydroxy vitamin D. Timepoint: Before and after interventions. Method of measurement: Using the ELISA method.;Interleukin-10. Timepoint: Before and after interventions. Method of measurement: Using the ELISA method.;Thyroid Stimulating Hormone. Timepoint: Before and after interventions. Method of measurement: immunochemiluminescence assay.;C-Reactive Protein. Timepoint: Before and after interventions. Method of measurement: Using the ELISA method.;Insulin. Timepoint: Before and after interventions. Method of measurement: Using the ELISA method.;Insulin resistance. Timepoint: Before and after interventions. Method of measurement: Using the homeostasis model(HOMA-IR).

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Secondary

Measure	Time frame
Glucose. Timepoint: Prior and after interventions. Method of measurement: Glucose oxidase assay.;Urea. Timepoint: Prior and after interventions. Method of measurement: Urease method.;Uric acid. Timepoint: Prior and after interventions. Method of measurement: Automatic colorimetric method.;Creatinine. Timepoint: Prior and after interventions. Method of measurement: Jaffe methods.;Triglyceride. Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.;Low-density lipoprotein cholesterol (LDL-C). Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.;High-density lipoprotein cholesterol (HDL-C). Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.;Total cholesterol. Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.;Aspartate aminotransferase. Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.;Alkaline phosphatase. Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.;Alanine aminotransferase. Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.	—

Measure

Time frame

Glucose. Timepoint: Prior and after interventions. Method of measurement: Glucose oxidase assay.;Urea. Timepoint: Prior and after interventions. Method of measurement: Urease method.;Uric acid. Timepoint: Prior and after interventions. Method of measurement: Automatic colorimetric method.;Creatinine. Timepoint: Prior and after interventions. Method of measurement: Jaffe methods.;Triglyceride. Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.;Low-density lipoprotein cholesterol (LDL-C). Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.;High-density lipoprotein cholesterol (HDL-C). Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.;Total cholesterol. Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.;Aspartate aminotransferase. Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.;Alkaline phosphatase. Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.;Alanine aminotransferase. Timepoint: Prior and after interventions. Method of measurement: Enzymatic method.

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Countries

Iran (Islamic Republic of)

Contacts

Public Contactmasoumeh habibian

Qaemshahr branch, Islamic Azad University

habibian_m@yahoo.com+98 11 4224 1041

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 16, 2026