The Effects of spinal stabilization and Vitamin D on the tumor necrosis factor-a and interleukin-10 in women with Chronic Low Back Pain

The Effects of spinal stabilization exercise and Vitamin D intake on the levels of tumor necrosis factor-a and interleukin-10 in women with Chronic Low Back Pain

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190831044650N1

Enrollment

Registered

2020-03-02

Start date

2019-12-30

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic low back pain.

Interventions

Intervention 1: Intervention group 1: Exercise group will perform 8 weeks of spinal stabilization exercises consisting of 3 sets of 8 stretching and isometric exercises with one minute rest between ex

Eligibility

Sex/Gender

Female

Age

30 Years to 50 Years

Inclusion criteria

Inclusion criteria: Having chronic low back pain for more than three months Pain score (based on visual analogue scale) moderate Not having regular exercise for the past six months

Exclusion criteria

Exclusion criteria: Use of specific drugs smoking Pregnancy

Design outcomes

Primary

Measure	Time frame
Tumor necrosis factor-a. Timepoint: Prior and after interventions. Method of measurement: Using the ELISA method.;Interleukin-10. Timepoint: Prior and after interventions. Method of measurement: Using the ELISA method.;C reactive protein. Timepoint: Prior and after interventions. Method of measurement: Using the ELISA method.;25- hydroxy vitamin D. Timepoint: Prior and after interventions. Method of measurement: Using the ELISA method.;Pain level. Timepoint: Prior and after interventions. Method of measurement: Visual Analogue Scale.;Severity of disability. Timepoint: Prior and after interventions. Method of measurement: the oswestry disability Questionnaire.;Sleep quality. Timepoint: Prior and after interventions. Method of measurement: Petersburg Sleep Questionnaire.;Quality of Life. Timepoint: Prior and after interventions. Method of measurement: SF-36 Quality of Life Questionnaire.	—

Measure

Time frame

Tumor necrosis factor-a. Timepoint: Prior and after interventions. Method of measurement: Using the ELISA method.;Interleukin-10. Timepoint: Prior and after interventions. Method of measurement: Using the ELISA method.;C reactive protein. Timepoint: Prior and after interventions. Method of measurement: Using the ELISA method.;25- hydroxy vitamin D. Timepoint: Prior and after interventions. Method of measurement: Using the ELISA method.;Pain level. Timepoint: Prior and after interventions. Method of measurement: Visual Analogue Scale.;Severity of disability. Timepoint: Prior and after interventions. Method of measurement: the oswestry disability Questionnaire.;Sleep quality. Timepoint: Prior and after interventions. Method of measurement: Petersburg Sleep Questionnaire.;Quality of Life. Timepoint: Prior and after interventions. Method of measurement: SF-36 Quality of Life Questionnaire.

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Secondary

Measure	Time frame
Aspartate aminotransferase. Timepoint: Before and after interventions. Method of measurement: Enzymatic method.;Alkaline phosphatase. Timepoint: Before and after interventions. Method of measurement: Enzymatic method.;Alanine aminotransferase. Timepoint: Before and after interventions. Method of measurement: Enzymatic method.;Urea. Timepoint: Before and after interventions. Method of measurement: Urease method.;Uric acid. Timepoint: Before and after interventions. Method of measurement: Automatic colorimetric method.;Creatinine. Timepoint: Before and after interventions. Method of measurement: Jaffe methods.;Triglyceride. Timepoint: Before and after interventions. Method of measurement: Enzymatic method.;Total cholesterol. Timepoint: Before and after interventions. Method of measurement: Enzymatic method.;Low-density lipoprotein cholesterol (LDL-C). Timepoint: Before and after interventions. Method of measurement: Enzymatic method.;High-density lipoprotein cholesterol (HDL-C). Timepoint: Before and after interventions. Method of measurement: Enzymatic method.	—

Measure

Time frame

Aspartate aminotransferase. Timepoint: Before and after interventions. Method of measurement: Enzymatic method.;Alkaline phosphatase. Timepoint: Before and after interventions. Method of measurement: Enzymatic method.;Alanine aminotransferase. Timepoint: Before and after interventions. Method of measurement: Enzymatic method.;Urea. Timepoint: Before and after interventions. Method of measurement: Urease method.;Uric acid. Timepoint: Before and after interventions. Method of measurement: Automatic colorimetric method.;Creatinine. Timepoint: Before and after interventions. Method of measurement: Jaffe methods.;Triglyceride. Timepoint: Before and after interventions. Method of measurement: Enzymatic method.;Total cholesterol. Timepoint: Before and after interventions. Method of measurement: Enzymatic method.;Low-density lipoprotein cholesterol (LDL-C). Timepoint: Before and after interventions. Method of measurement: Enzymatic method.;High-density lipoprotein cholesterol (HDL-C). Timepoint: Before and after interventions. Method of measurement: Enzymatic method.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoumeh Habibian

Qaemshahr branch, Islamic Azad University

habibian_m@yahoo.com+98 11 4224 1041

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026