Preeclampsia. Pre-eclampsia
Conditions
Interventions
Intervention 1: Intervention group: Pregnant women who will take aspirin 160 mg.The 80 mg Aspirin by the Jalinus Pharmaceutical Company will be used orally 2 times a day from the time of study until t
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: The pregnant mother has completed the consent form to participate in the study. Pregnant mother is 12 to 16 weeks pregnant. The pregnant mother has at least one of the following criteria: a history of previous preeclampsia, polygamy, chronic hypertension, type 1 and type 2 diabetes, kidney disease, autoimmune disease (such as lupus). Or the pregnant mother has at least two of the following criteria: nulliparity, obesity, age over 35, low level of socioeconomic status, gap between pregnancies over 10 years, adverse pregnancy outcome (stillbirth, etc.)
Exclusion criteria
Exclusion criteria: The pregnant mother has peptic ulcer. The pregnant mother has gout.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preeclampsia. Timepoint: Each 2 week from 20 to 28 weeks of gestational age and after that weekly until the termination of pregnancy. Method of measurement: Systolic blood pressure greater than 1 mmHg or diastolic blood pressure greater than 1 mmHg. | — |
Secondary
| Measure | Time frame |
|---|---|
| Preterm delivery. Timepoint: Mother's delivery. Method of measurement: Maternal gestational age is less than 37 weeks.;Method of childbirth. Timepoint: Mother's delivery. Method of measurement: Cesarean section or Vaginal delivery.;Intrauterine fetal growth restriction. Timepoint: Every two weeks from the start of the intervention until the 28th week of pregnancy. Method of measurement: sonography.;Apgar score minute1. Timepoint: 1 minute after birth. Method of measurement: Grading to Appearance, Pulse, Grimace, Activity and Respiration of baby.;Apgar score minute 5. Timepoint: 5 minutes after birth. Method of measurement: Grading to Appearance, Pulse, Grimace, Activity and Respiration of baby. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Chamani
Iran University of Medical Sciences
Outcome results
None listed