Skip to content

The effect of metoclopramide on postoperative pain and nausea

The effect of intravenous infusion and subcutaneous infiltration of metoclopramide on postoperative pain and nausea in lower abdominal surgery comparison with control group

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190825044609N1
Enrollment
75
Registered
2019-09-14
Start date
2017-04-21
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Postoperative pain. Condition 2: Postoperative nausea.

Interventions

Intervention 1: Intervention group 1: Intravenous injection of 0.15mg/kg metoclopramide in 5 cc normal saline and subcutaneous injection of 5cc normal saline. Intervention 2: Intervention group 2: S

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients aged 18-65 year referred to Al-Zahra hospital during the year 1396-1397 for elective lower abdominal surgery and classified as ASA physical status 1 & 2 were included

Exclusion criteria

Exclusion criteria: Pregnancy Addiction to cigarette, opioid and alcohol Weight over 100 kg Allergy to metoclopramide Chronic pain that lasts more than 6 months Anxiety before surgery Taking any analgesic 24 hours before surgery

Design outcomes

Primary

MeasureTime frame
Intensity of postoperative pain. Timepoint: In extubation time, 15 minutes, 30 minutes, 60 minutes, 2 hours, 4 hours, 8 hours, 16 hours, 24 hours after surgery. Method of measurement: Questionnaire according to Visual Analogue Scale.;Intensity of postoperative nausea. Timepoint: In extubation time, 15 minutes, 30 minutes, 60 minutes, 2 hours, 4 hours, 8 hours, 16 hours, 24 hours after surgery. Method of measurement: Questionnaire according to Visual Analogue Scale.

Secondary

MeasureTime frame
Blood pressure. Timepoint: In extubation time, 15 minutes, 30 minutes, 60 minutes, 2 hours, 4 hours, 8 hours, 16 hours, 24 hours after surgery. Method of measurement: manometer.;Heart rate. Timepoint: In extubation time, 15 minutes, 30 minutes, 60 minutes, 2 hours, 4 hours, 8 hours, 16 hours, 24 hours after surgery. Method of measurement: pulseoxymeter.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Haji Gholam Saryazdi

Esfahan University of Medical Sciences

haji@med.mui.ac.ir+98 31 3637 0416

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026