Idiopathic male infertility. Male infertility, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Group of patients receiving a single capsule (500 mg) of FamiLact daily (after meal). Each capsule of FamiLact contains bacterial strains of Lactobacillus rhamnosus
Sponsors
Artesh University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Infertile men with abnormal sperm analysis due to unknown underlying cause
Exclusion criteria
Exclusion criteria: Cryptorchidism Varicocele Chromosome abnormalities Leukocytospermia Epididymo-orchitis History of trauma to genitourinary system Prostatitis History of testicular torsion Previous inguinal surgeries History of Hormonetherapy History of endocrinopathies History of medication with cytotoxic drugs, immunosuppressants, androgens, and anticonvulsants Recent sexually transmitted infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sperm concentration. Timepoint: Evaluating sperm concentration before and 80 days after probiotic administration. Method of measurement: Semen sample analysis.;Semen volume. Timepoint: Evaluating semen volume before and 80 days after probiotic administration. Method of measurement: Semen sample analysis.;Percentage of abnormal sperm morphology. Timepoint: Evaluating the percentage of abnormal sperm morphology before and 80 days after probiotic administration. Method of measurement: Semen sample analysis.;Percentage of sperm motility. Timepoint: Evaluating the percentage of motile sperm before and 80 days after probiotic administration. Method of measurement: Semen sample analysis.;Percentage of sperm progressive motility. Timepoint: Evaluating the percentage of sperm progressive motility before and 80 days after probiotic administration. Method of measurement: Semen sample analysis.;Percentage of sperm lipid peroxidation. Timepoint: Evaluating the percentage of sperm lipid peroxidation before and 80 days after probiotic administration. Method of measurement: Semen sample analysis.;Intensity of sperm lipid peroxidation. Timepoint: Evaluation the intensity of sperm lipid peroxidation before and 80 days after probiotic administration. Method of measurement: Semen sample analysis.;Percentage of sperm DNA damage index. Timepoint: Evaluating the percentage of sperm DNA damage index before and 80 days after probiotic administration. Method of measurement: Semen sample analysis (SCSA test).;Percentage of sperm protamine deficiency. Timepoint: Evaluating the percentage of sperm protamine deficiency before and 80 days after probiotic administration. Method of measurement: Semen sample analysis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBehzad Abbasi
Artesh University of Medical Sciences
Outcome results
None listed