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Effect of Atorvastatin in Helicobacter pylori eradication

Evaluation of the effect of adding Atorvastatin to standard treatment in Helicobacter pylori eradication

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190823044589N1
Enrollment
120
Registered
2019-12-28
Start date
2019-04-21
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection.

Interventions

Intervention 1: Intervention group: Atrostatin 40 mg at night for 14 days with standard treatment (including a Bismuth Subcitrate 240 mg tablet, a Pantoprazole 40 mg tablet, a metronidazole 500 mg tab

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 18 years or older Indication for Helicobacter pylori eradication

Exclusion criteria

Exclusion criteria: liver disease at the same time Diabetes at the same time Statin use in 6 months History of gastric surgery History of treatment for eradication of H. pylori Antibiotics, PPIs, histamine receptor blockers, anti-inflammatory and non-steroidal drugs, bismuth salts in the past month Allergy to any of the antibiotics used in the study Gastrointestinal malignancy Active gastrointestinal bleeding Pregnant and lactating History of radiation therapy

Design outcomes

Primary

MeasureTime frame
Helicobacter pylori eradication. Timepoint: After 4 weeks of completion of treatment. Method of measurement: 38/5000Evaluation of Helicobacter pylori fecal antigen.

Secondary

MeasureTime frame
Drug Side effects. Timepoint: During and after the course of treatment. Method of measurement: Ask the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Mohammad Hosseini Azar

Oroumia University of Medical Sciences

mohammadazar@gmail.com+98 44 3346 9931

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026