Skip to content

Effect of oral Magnesium oxide on preoperative analgesia in hysterectomy

Comparing the preoperative analgesia effects of oral Magnesium oxide and Naproxen for hysterectomy surgery in Afzalipour hospital , Kerman, 2019

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190819044559N1
Enrollment
64
Registered
2019-11-04
Start date
2019-08-13
Completion date
Unknown
Last updated
2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after hysterectomy surgery. Other acute postprocedural pain

Interventions

Intervention 1: Intervention group: receiving oral Magnesium oxide (500 mg) 1.5 hour before surgery. Intervention 2: Control group: receiving oral Naproxen (500 mg)1.5 hour before surgery.

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
35 Years to 65 Years

Inclusion criteria

Inclusion criteria: No history of sensitivity to magnesium and naproxen Lack of liver diseases No kidney or cardiovascular dysfunction no lactation age between 35 to 65

Exclusion criteria

Exclusion criteria: drug or opiod addiction neurological disorder, pain or abuse of opiod analgesic Concomitant treatment with analgesics or anti-inflammatory drugs Chronic treatment with magnesium or calcium channel blockers Patients with complicated appendectomy

Design outcomes

Primary

MeasureTime frame
Pain score after hysterectomy surgery. Timepoint: After surgery and consciousness of the patient. Method of measurement: VAS scale.;Pulse rate changes. Timepoint: During operation. Method of measurement: Arm cuff.;Blood pressure changes. Timepoint: During operation. Method of measurement: Arm cuff.;Time between end of operation and first prescription of analgesics. Timepoint: The first time that patient need analgesic. Method of measurement: patient demand.

Secondary

MeasureTime frame
Chill feeling. Timepoint: After operation. Method of measurement: Clinical symptoms.;Nausea. Timepoint: After operation. Method of measurement: Clinical symptoms.;Vomiting. Timepoint: After operation. Method of measurement: Clinical symptoms.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMorteza Hashemian

Kerman University of Medical Sciences

Mortezahashemian@kmu.ac.ir+98 34 3211 3012

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026