Effect of Vitamin D on neonatal respiratory distress

Comparison of the incidence of respiratory distress syndrome in neonates of mothers receiving vitamin D with those who do not receive

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190814044529N1

Enrollment

100

Registered

2020-01-21

Start date

2019-01-15

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neonatal respiratory distress. Respiratory distress syndrome of newborn

Interventions

Intervention 1: Intervention group: In this group mothers will receive vitamin D injections(50,000 IU) 72 hours before childbirth. Intervention 2: Control group: No intervention including injection of

Eligibility

Sex/Gender

All

Age

No minimum to 238 Days

Inclusion criteria

Inclusion criteria: All singleton pregnant women with a gestational age of less than 34 weeks, at risk of preterm delivery

Exclusion criteria

Exclusion criteria: Cardiovascular diseases (except for preeclampsia /eclampsia) Asthma History of certain illicit and prescription drugs(including narcotics, antiepileptic, non-steroid anti-inflammatory drugs, sedative-hypnotics, and tocolytics) Multiple gestations

Design outcomes

Primary

Measure	Time frame
Neonatal respiratory distress reduction. Timepoint: 1-3 days after neonatal birth. Method of measurement: RDS will be diagnosed according to clinical criteria (tachypnea, subarachnoid retraction, grunting, groaning) and radiological criteria (volume reduction , Ground-glass, fading border of diaphragm and heart shadow).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHasan Bosk abadi

Mashhad University of Medical Sciences

Boskabadih@mums.ac.ir+98 51 3840 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026