Comparison between oral irrigation with Echinacea mouthwash and chlorhexidine

A clinical comparison between oral irrigation with Echinacea extract as mouthwash and chlorhexidine (0.12%) in chronic periodontitis patients.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190813044525N1

Enrollment

Registered

2019-09-14

Start date

2019-08-13

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic periodontitis. Chronic periodontitis

Interventions

Intervention 1: Intervention group: Echinacea mouthwash (extract will be purchase from Zarband company and will be diluted with water to achieve .01% phenol as active compartment) will be given to the

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Presence of minimum of 22 teeth. Moderate or severe chronic periodontitis.

Exclusion criteria

Exclusion criteria: Patients with history of adverse reaction to chlorhexidine. Antibiotic therapy during last 2 months. Periodontal treatment during last 6 months. Diabetes. Pregnancy. Lactation. Tooth brushing more than 4 time per day. Smoking

Design outcomes

Primary

Measure	Time frame
1. Measuring Pocket depth (PD) . Timepoint: At base line and after 28 day. Method of measurement: William probe.;.2. Bleeding index (BI). Timepoint: At base line and after 28 day. Method of measurement: Lenox method by probe.;3. Plaque index (PI). Timepoint: At base line and after 28 day. Method of measurement: modified O'Leary method by disclosing agents.;4. Gingival index (GI). Timepoint: At base line and after 28 day. Method of measurement: Loe and Sillness method.	—

Measure

Time frame

1. Measuring Pocket depth (PD) . Timepoint: At base line and after 28 day. Method of measurement: William probe.;.2. Bleeding index (BI). Timepoint: At base line and after 28 day. Method of measurement: Lenox method by probe.;3. Plaque index (PI). Timepoint: At base line and after 28 day. Method of measurement: modified O'Leary method by disclosing agents.;4. Gingival index (GI). Timepoint: At base line and after 28 day. Method of measurement: Loe and Sillness method.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Sadegh Karami

Shiraz University of Medical Sciences

karamims@sums.ac.ir+98 71 3646 6378

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026