Patients with bipolar disorder. Bipolar disorder
Conditions
Interventions
Intervention 1: Intervention group: The intervention group received 16 mg daily silymarin in addition to standard treatments effective in the depression phase of bipolar disorder. Intervention 2: Cont
Sponsors
Hamedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Age group 18 to 70 years Patients with diagnosis of bipolar depression disorder by a psychiatrist based on DSM-5 Patients who receiving lithium
Exclusion criteria
Exclusion criteria: Patients with mixed depressive phase with simultaneous manic or hypomanic Pregnant patients Lactating patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thyroid markers. Timepoint: Before the intervention and 16 weeks after the intervention. Method of measurement: Using the ELISA method.;Serum antioxidant capacity. Timepoint: Before the intervention and 16 weeks after the intervention. Method of measurement: Using the Colorimetric Kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| The mean of liver parameters. Timepoint: Before intervention and 16 weeks after the intervention. Method of measurement: Using a special kit.;Blood lithium level. Timepoint: Before intervention and 16 weeks after the intervention. Method of measurement: By the fluorometric method.;Depression Phase Bipolar Disease. Timepoint: Before intervention and 16 weeks after the intervention. Method of measurement: Patient symptoms and physician diagnosis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSara Ataei
Hamedan University of Medical Sciences
Outcome results
None listed