Idiopathic oligoasthenospermia.
Conditions
Interventions
Intervention 1: Intervention group:They receive FamiLact capsules once a day for 4 weeks. Intervention 2: Control group: They receive placebo once a day for 4 weeks.
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Age 20 to 50 years Sperm concentration below 15 million per cc Percentage of progressive motile spermatozoa < 32% Total ejaculated spermatozoa<39*106 Total motility <40% Normal serum levels of free testosterone, Prolactin, Luteinizing hormone, Follicle-stimulating hormone
Exclusion criteria
Exclusion criteria: Drug or alcohol abuse Concentration of white blood cells in semen > 106 per cc Possibility of being treated with gonadotropins, anabolic steroids, cancer chemotherapy, NSAIDs, infertility medications in the last two months Previous history of chemotherapy or radiotherapy for cancer Existence of palpable varicocele X-ray history of the past eight months Y chromosome microdeletion Karyotype alterations Testicular atrophy and testicular failure Other secondary causes of infertility A history of liver problems and a history of allergy to clomiphene Percentage of typical forms<4% Ejaculated volume <1.5 ml Abnormal serum levels of free testosterone, Prolactin, Luteinizing hormone, Follicle-stimulating hormone
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sperm concentration in semen. Timepoint: Before the intervention and after the intervention. Method of measurement: Spermatogram test.;Sperm motility in semen. Timepoint: Before the intervention and after the intervention. Method of measurement: Spermatogram test.;Sperm morphology in Semen. Timepoint: Before the intervention and after the intervention. Method of measurement: Spermatogram test.;Semen fluid volume. Timepoint: Before the intervention and after the intervention. Method of measurement: Spermatogram test.;Semen fluid Power Hydrogen. Timepoint: Before the intervention and after the intervention. Method of measurement: Spermatogram test.;Serum concentration of free testosterone, prolactin, luteinizing hormone, follicle-stimulating hormone. Timepoint: Before the intervention and after the intervention. Method of measurement: Blood test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Age. Timepoint: Before the intervention and after the intervention. Method of measurement: Questionnaire.;Height. Timepoint: Before the intervention and after the intervention. Method of measurement: Questionnaire.;Weight. Timepoint: Before the intervention and after the intervention. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Saghafi
Yazd University of Medical Sciences
Outcome results
None listed