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Evaluation of the effectiveness and safety of PMSoff natural supplement for improving premenstrual syndrome (PMS)

Evaluation of the effectiveness and safety of PMSoff natural supplement for improving premenstrual syndrome (PMS): A randomized double blind placebo control clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190810044500N30
Enrollment
102
Registered
2025-03-02
Start date
2024-02-20
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PMS( Pre menstrual syndrome. Other specified conditions associated with female genital organs and menstrual cycle

Interventions

Intervention 1: Intervention group: The natural supplement is PMSoff, which is in caplet form and is 1000 mg. The participants of the study are asked to take the medicine twice a day, morning and nigh

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
14 Years to 30 Years

Inclusion criteria

Inclusion criteria: Women between the ages of 14 to 30 Women with premenstrual syndrome diagnosed by PSST tool Consent of at least one parent to participate in the study for girls under 18

Exclusion criteria

Exclusion criteria: The presence of chronic diseases History of pelvic inflammatory disease Hysterectomy surgery Not suffering from premenstrual syndrome based on the PSST tool Having mental problems

Design outcomes

Primary

MeasureTime frame
Mean score of severity of premenstrual syndrome symptoms. Timepoint: One month and two months before the start of the intervention and also one month and two months after the intervention. Method of measurement: using DSRP score.;Patient compliance. Timepoint: One month and two months before the start of the intervention and also one month and two months after the intervention. Method of measurement: Using Morisky medication adherence scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Saghafi

Yazd University of Medical Sciences

F.saghafi@ssu.ac.ir+98 35 3820 3419

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026