Mucositis. Diseases of the digestive system
Conditions
Interventions
Intervention 1: Intervention group1: patients will be received 0.1% curcumin mouthwash 3 times a day for 3 weeks. Intervention 2: Intervention group 2: patients will be received curcumin capsule 40 m
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with mucositis caused by radiotherapy and chemotherapy Get at least a dose of 50 gray of radiation during the study At least two parts of the mouth are involved
Exclusion criteria
Exclusion criteria: Patients with certain diseases Unwillingness to continue participating in the study smoking Serious dental problems, bruising teeth and the presence of sharp fillings Presence of artificial teeth importing trauma Severe systemic disease such as uncontrolled diabetes With the start of radiation therapy, the patient should be treated by a physician other than for the usual treatment for mucositis. Simultaneous treatment with Target therapy drugs Infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oral wound size. Timepoint: Before the intervention, after completion of the intervention. Method of measurement: Clinical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain or burning sensation in the mouth. Timepoint: Before intervention, after intervention. Method of measurement: Clinical examination and patient based on VAS criteria.;Redness. Timepoint: Before intervention, after intervention. Method of measurement: Clinical examination and patient based on VAS criteria. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactshiva ghadirian abarghoyi
Yazd University of Medical Sciences
Outcome results
None listed