COVID-19 pneumonia. Covid-19 disease
Conditions
Interventions
Intervention 1: Intervention group: all the patients received remdesivir (200 mg on the first day followed by 100 mg daily for five days and, corticosteroid therapy ( Dexamethasone 8 mg or equivalent
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Hospitalization with oxygen saturation less than 94% COVID-19 diagnosis according to chest CT scan or RT-PCR
Exclusion criteria
Exclusion criteria: Pregnancy lactating women Severe liver failure (Child-pugh C) or liver enzymes more than 3 times normal Renal failure (glomerular filtration less than 30 ml / min) Chronic use of immunosuppressive drugs or corticosteroids Absolute lymphocyte count less than 500 per cubic millimeter Absolute neutrophil counts less than 1000 per cubic millimeter
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improving the clinical symptoms of patients with covid-19. Timepoint: Day one, day seven, day 14, day 28. Method of measurement: eight-category ordinal scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality rate. Timepoint: During hospitalization and on days 14 and 28. Method of measurement: Observation.;Admission in intensive care units. Timepoint: During hospitalization. Method of measurement: Observation.;Ventilator need. Timepoint: During hospitalization. Method of measurement: Observation.;Incidence of possible side effects. Timepoint: During hospitalization. Method of measurement: Observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMonireh Ghazaeian
Mazandaran University of Medical Sciences
Outcome results
None listed