Acute ischemic stroke. Cerebral infarction
Conditions
Interventions
Intervention 1: Intervention group: In addition to receiving standard enteral nutrition (high-protein fast meal powder), they will receive MCT oil at a dose of 1 gram per kilogram of body weight per d
Sponsors
Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Male and female over 18 years of age with a diagnosis of acute ischemic stroke NIHSS score 5 to 24 Ability to receive enteral nutrition via gavage or oral route
Exclusion criteria
Exclusion criteria: Pregnancy and Lactation Patients with severe liver failure Child-class C Patients with severe renal failure CLCr<30 ml/min Brain tumor or Brain abscess Hemorrhagic stroke More than 24 hours have passed since the patient's ischemic stroke History of allergy to coconut or MCT oil
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glutathione serum level. Timepoint: Day 0 and 4 of the study. Method of measurement: Spectroscopy.;Antioxidant serum levels. Timepoint: Day 0 and 4 of the study. Method of measurement: Spectroscopy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Disability following stroke. Timepoint: Day 0 and 4 of the study. Method of measurement: Based on the mRS criterion.;Change in ischemic area volume in CT scan imaging. Timepoint: Day 0 and 4 of the study. Method of measurement: CT scan - Imaging.;Tolerability of MCT oil. Timepoint: During the study period. Method of measurement: History taking.;Improving the patient's physical function. Timepoint: at days 0 and 4th of the study. Method of measurement: NIHSS score.;Metabolic changes including fasting and random blood glucose and lipid profile. Timepoint: at days 0 and 4th of the study. Method of measurement: Laboratory parameters. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMonireh Ghazaeian
Mazandaran University of Medical Sciences
Outcome results
None listed