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Effects of Saffron (Crocus sativus L.) supplementation and Combined Training in obese men with T2DM

Effects of Saffron (Crocus sativus L.) supplementation and Combined Training on Physiological Regulators in obese men with T2DM

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190731044398N4
Enrollment
60
Registered
2020-07-25
Start date
2020-05-30
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: type 2 diabetes. Condition 2: obesity. Non-insulin-dependent diabetes mellitus obesity

Interventions

Intervention 1: Intervention group: The training group performed 12 weeks and each week 3 sessions of combined training (Resistance training, Aerobic training). Resistance training (Three sets / six e

Sponsors

Vice Chancellor For Research, Ferdowsi University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
30 Years to 50 Years

Inclusion criteria

Inclusion criteria: age 30-50 years BMI > 30 kg/m2 fasting blood glucose = 126 mg/dL HbA1C = 6.5%

Exclusion criteria

Exclusion criteria: use insulin having cardiovascular diseases, musculoskeletal disorders, liver disease, kidney disease, and thyroid dysfunction having regular physical activity in the past year Not taking dietary supplements Sensitivity to saffron

Design outcomes

Primary

MeasureTime frame
Fasting insulin. Timepoint: Before and after intervention. Method of measurement: Autoanalyzer kit.;Serum levels of testosterone. Timepoint: Before and after intervention. Method of measurement: Blood sampling and using ELISA method.;Serum levels of Nitric oxide. Timepoint: Before and after intervention. Method of measurement: Blood sampling and using ELISA method.;Serum levels of hs-CRP. Timepoint: Before and after intervention. Method of measurement: Blood sampling and using ELISA method.;Serum levels of TNF-a. Timepoint: Before and after intervention. Method of measurement: Blood sampling and using ELISA method.;Serum levels of IL-6. Timepoint: Before and after intervention. Method of measurement: Blood sampling and using ELISA method.;Serum levels of IL-10. Timepoint: Before and after intervention. Method of measurement: Blood sampling and using ELISA method.;Serum levels of adiponectin. Timepoint: Before and after intervention. Method of measurement: Blood sampling and using ELISA method.;Serum levels of leptin. Timepoint: Before and after intervention. Method of measurement: Blood sampling and using ELISA method.;Serum levels of Chemerin. Timepoint: Before and after intervention. Method of measurement: Blood sampling and using ELISA method.

Secondary

MeasureTime frame
Fat mass. Timepoint: Before and after intervention. Method of measurement: bioelectrical impedance device.;Fat free mass. Timepoint: Before and after intervention. Method of measurement: bioelectrical impedance device.;Dietary intake. Timepoint: Before and after intervention. Method of measurement: Food record questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactamir rashidlamir

Ferdowsi University of Mashhad

amir.rashidlamir@um.ac.ir+98 51 3880 5000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026