Effect of cryopercipitate in trauma patients with brain contusion

Clinical trial to compare the effect of cryopericiptate and conventional treatment on prevention of brain contusion expansion in trauma patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190729044375N1

Enrollment

Registered

2021-01-31

Start date

2021-02-08

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain contusion expansion in traumatic patients(ICH

Interventions

Intervention 1: Intervention group: In addition to receivig conservative routine care

intravenous adminestration of 4 units of cryoprecipitate prepared in Iranian Blood Transfusion Organization which contains coagulation factors (fibrinogen& 8&13&VWF) in nonpregnant traumatic patient

above18y/o and have no history of blood factor deficiency disease are only under routine conservative care(ICU admission and control of GCS and anticonvulsant therapy).

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Traumatic brain contusion or brain hematoma Over 18 years of age Their legal guardian allowance

Exclusion criteria

Exclusion criteria: History of blood hemostatic factor deficiency Candidate for emergency brain hemorrhage surgery Pregnancy

Design outcomes

Primary

Measure	Time frame
Size of brain tissue hematoma. Timepoint: At the time of admission and 6, 12, 24 and 48 hours after admission. Method of measurement: Size determination on CT scan graph by radiologist.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Mohamamdreza Akrami

Kermanshah University of Medical Sciences

alireza.tahmoures@gmail.com+98 83 3837 8098

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026