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Comparison the effects of Acetaminophen and Ibuprofen on emotions

Comparison the effects of Acetaminophen and Ibuprofen on emotions by recording electrical activity of the brain

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190729044367N1
Enrollment
54
Registered
2020-08-31
Start date
2020-08-05
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers. Other symptoms and signs involving emotional state

Interventions

In the first stage, participants are given a brain signal for each emotional state (happiness-sadness-neutral) while listening to a three-minute music. Before and after listening to music, each person

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: All participants should be right-handed They have normal hearing sensitivity No reported history of brain diseases like depression or alzheimer. No head trauma, stroke or injury Do not have history of alcohol and smoking (especially a few days before the signal is recorded)

Exclusion criteria

Exclusion criteria: Pregnancy Breastfeeding Preexisting neurological or psychological disorders Severe liver failure based on Child-Pugh Score Renal failure (Glomerular Filtration Rate (GFR) < 15 mL/min) History of prior anti-psychotic or anti-epileptic use Allergy to oral Acetaminophen and non-steroidal anti-inflammatory drug (NSAID) History of smoking or alcohol abuse

Design outcomes

Primary

MeasureTime frame
Emotional arousal score in questionnaire between 0-5. Timepoint: Survey the emotional state immediately after the recording for checking the effect of painkiller. Method of measurement: Asking participants after recording and score the music from 0-5. and observe and analyze brain signals in both happiness and sadness.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNeda Kaffash

Islamic Azad University

neda.kaffash@yahoo.com+98 21 4401 2937

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026