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The effectiveness of N-acetylcystein (NAC) on accelerating renal failer recovery

The effectivenees of N-acetylcysteine (NAC) on accelerating renal failer recovery in patient with leptospirosis in Razi Hospital of Ghaemshahr city 2019

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190727044343N4
Enrollment
64
Registered
2020-07-28
Start date
2019-05-05
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Leptospirosis - Acute renal failer. Leptospirosis

Interventions

Intervention 1: Intervention group:The group to individual number is assigned is treated with N-acetylcystein 1200mg every 12 hours for 48 hours po. Pharmaceutical production

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: People with Glomerular Filteration Rate (GFR) have less than 60 studies. People whose leptospirosis has been confirmed by Enzym-Linked Immunosorbent Assay (ELISA) or Microscopic Agglutination Test (MAT) . Satisfaction to participate in the study.

Exclusion criteria

Exclusion criteria: Diabetics are excluded from the study. People with underlying liver disease are excluded from the study. People with underlying kidney disease excluded from the study. Patients who have been hospitalized with sepsis symptoms prior to refferal.

Design outcomes

Primary

MeasureTime frame
Decreased mean serum creatinine levels. Timepoint: Measurement of serum creatinine levels on days 0,3 and 7 after initiation of treatment. Method of measurement: Blood serum sample.

Secondary

MeasureTime frame
Improved glomerular filtration rate. Timepoint: 0,3and days to start treatment. Method of measurement: Blood serum sample.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLotfollah Davoodi

Mazandaran University of Medical Sciences

lotfdavoodi@yahoo.com+98 11 4221 8231

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026