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Effect of Calci-Herb Supplement on Opioid Withdrawal Symptoms

Effect of Calci-Herb Supplement on Opioid Withdrawal Symptoms A Randomized Triple-Blind Placebo-Controlled Clinical Trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190726044339N6
Enrollment
60
Registered
2026-05-06
Start date
2026-05-15
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

substance use disorder. Opioid related disorders

Interventions

Intervention 1: Intervention group: Intervention group: Participants will receive daily calci-herb supplements. Intervention 2: Control group: Participants will receive two placebo capsules daily.

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Having opioid use disorder in the acute withdrawal phase Age between 18 and 70 years Providing written informed consent Willingness to participate in the study and continue follow-up until completion

Exclusion criteria

Exclusion criteria: Presence of serious and chronic diseases Severe mental disorders Inability to comply with the study protocol

Design outcomes

Primary

MeasureTime frame
Pain Severity. Timepoint: At the beginning of the study (before the intervention) and 7, 141 days after starting Calciherb. Method of measurement: Visual pain scale.;Clinical Opiate Withdrawal Severity. Timepoint: At the beginning of the study (before the intervention) and 7, 141 days after starting Calciherb. Method of measurement: Clinical Opiate Withdrawal Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Hamdollah Mosavat

Shiraz University of Medical Sciences

hamdi_88114@yahoo.com+98 917 840 1495

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026