Efficacy of chitoson on salivary Streptococcus mutans counts and salivary pH

Comparison the efficacy of chitoson-based gum and ordinary gum on salivary Streptococcus mutans counts and salivary pH in dentistry students of Hamadan University of Medical Sciences : a randomised clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190724044319N1

Enrollment

Registered

2019-08-12

Start date

2019-09-23

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries. Diseases of oral cavity, salivary glands and jaws

Interventions

Intervention 1: Intervention group: 10% chitoson-based chewing gum, manufactured by Sigma-Aldrich company from Iceland, 8 times (5 minutes for each time) used by the contributor. Intervention 2: Cont

Eligibility

Sex/Gender

All

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Being student at faculty of Dentistry, Hamadan University of Medical Sciences Being in the age range of 18-30 years old Having moderate to good oral health status Having at least 24 healthy teeth

Exclusion criteria

Exclusion criteria: Having an orthodontic and prosthetic device in the mouth Having symptoms of periodontal disease Having systemic disease Being smoker Being mouthwash user Using antibiotics over the last six months

Design outcomes

Primary

Measure	Time frame
Salivary Streptococcus mutans counts. Timepoint: 80 minutes after beginning intervention. Method of measurement: colony counter device.;Changes in salivary pH. Timepoint: 80 minutes after beginning intervention. Method of measurement: Strip method.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Khamverdi

Hamedan University of Medical Sciences

zkhamverdi@yahoo.com+98 81 3838 1894

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 25, 2026