Chronic Kidney Disease. Chronic kidney disease (CKD)
Conditions
Interventions
Intervention 1: Intervention group: After entering the trial, patients will be prescribed to take co enzyme Q10 supplement from Nutri Century Corporation 3 mg per kg up to 100 mg daily adjuvant to the
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
2 Years to 18 Years
Inclusion criteria
Inclusion criteria: Age between 2 to 18 years old Diagnosed with Chronic Kidney Disease stage 2 - 4 according to estimated Glomerular Filtration Rate (eGFR) findings
Exclusion criteria
Exclusion criteria: Liver disease Chronic pulmonary disease Autoimmune disease Gastrointestinal dysfunction with the need for Parenteral nutrition Kidney transplantation in last 6 months Taking Antioxidants such as Vit E , L-Carnitine, or Omega 3 supplements in past 3 months Taking corticosteroids and/or immunosuppressive medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood Urea Nitrogen level. Timepoint: Before starting an intervention and three months after taking co enzyme Q10 supplement. Method of measurement: Blood test, Photometric kit.;Creatinine level. Timepoint: Before starting an intervention and three months after taking co enzyme Q10 supplement. Method of measurement: Blood test, photometric kit.;EGFR. Timepoint: Before starting an intervention and three months after taking co enzyme Q10 supplement. Method of measurement: Calculation based on blood Creatinine and patient's height.;Proteinuria. Timepoint: Before starting an intervention and three months after taking co enzyme Q10 supplement. Method of measurement: Urine test, Dipstick. | — |
Secondary
| Measure | Time frame |
|---|---|
| Aspartate Aminotransferase (AST) level. Timepoint: Before starting the intervention and 3 months after taking co enzyme Q10 supplement. Method of measurement: Blood test, photometric kit.;Blood Triglyceride level. Timepoint: Before starting the intervention and 3 months after taking co enzyme Q10 supplement. Method of measurement: Blood test, photometric kit.;Low Density Lipoprotein (LDL) level. Timepoint: Before starting the intervention and 3 months after taking co enzyme Q10 supplement. Method of measurement: Blood test, photometric kit.;High Density Lipoprotein (HDL) level. Timepoint: Before starting the intervention and 3 months after taking co enzyme Q10 supplement. Method of measurement: Blood test, photometric kit.;Total Cholesterol level. Timepoint: Before starting the intervention and 3 months after taking co enzyme Q10 supplement. Method of measurement: Blood test, photometric kit.;Urine protein level. Timepoint: Before starting the intervention and 3 months after taking co enzyme Q10 supplement. Method of measurement: Urine test, Dipstick method.;C-Reactive Protein (CRP) level. Timepoint: Before starting the intervention and 3 months after taking co enzyme Q10 supplement. Method of measurement: Blood test, Agglutination method.;Erythrocyte Sedimentation Rate (ESR) level. Timepoint: Before starting the intervention and 3 months after taking co enzyme Q10 supplement. Method of measurement: Blood test, Photometric kit.;Fasting blood Glucose level. Timepoint: Before starting the intervention and 3 months after taking co enzyme Q10 supplement. Method of measurement: Blood test, Photometric test.;Alanine Aminotransferase (ALT) level. Timepoint: Before starting the intervention and 3 months after taking co enzyme Q10 supplement. Method of measurement: Blood test, photometric kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactPedram Shayesteh
Iran University of Medical Sciences
Outcome results
None listed