The effects of three different doses of sufentanil on changes in blood pressure and heart rate after laryngoscopy and intubation

The effects of three different doses of sufentanil on changes in blood pressure and heart rate after laryngoscopy and intubation and comparison with the control group

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190721044298N1

Enrollment

128

Registered

2020-01-29

Start date

2019-04-21

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effect of sufentanil on heart rate, the effect of sufentanil on blood pressure. Adverse effect of intravenous anesthetics

Interventions

Intervention 1: First intervention group: Sufentanil recipient at a dose of 0.1 µg / kg. Intervention 2: Second intervention group: Suffentanil recipient at a dose of 0.2 µg / kg. Intervention 3: Thir

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: patient with ASA I-II that have 18 to 65 years old have elective surgery with general anesthesia with intubation

Exclusion criteria

Exclusion criteria: history of cardiovascular disease renal failure anti hypertension drug airway abnormality patient with difficult intubation possibility addiction

Design outcomes

Primary

Measure	Time frame
Heart rate in laryngoscopy and intubation. Timepoint: At baseline, immediately before laryngoscopy, 1, 3, 5 and 10 minutes after laryngoscopy. Method of measurement: Heart monitor.;Blood pressure in laryngoscopy and intubation. Timepoint: At baseline, immediately before laryngoscopy, 1, 3, 5 and 10 minutes after laryngoscopy. Method of measurement: Digital barometer device connected to the monitor.	—

Measure

Time frame

Heart rate in laryngoscopy and intubation. Timepoint: At baseline, immediately before laryngoscopy, 1, 3, 5 and 10 minutes after laryngoscopy. Method of measurement: Heart monitor.;Blood pressure in laryngoscopy and intubation. Timepoint: At baseline, immediately before laryngoscopy, 1, 3, 5 and 10 minutes after laryngoscopy. Method of measurement: Digital barometer device connected to the monitor.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Iravani

Esfahan University of Medical Sciences

kashani@mui.ac.ir+98 31 3233 0091

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026