Effect of vitramin D in asthma

The effect of vitamin D on pulmonary function and serum level of interleukin 10 and antioxidant activity in patient with moderate to severe asthma.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190721044288N1

Enrollment

Registered

2020-10-27

Start date

2019-04-19

Completion date

Unknown

Last updated

2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma. Asthma

Interventions

Intervention 1: Control group: received 1 pearl containing glucose daily (made by Birjand School of Pharmacy) as a placebo for 3 months. Intervention 2: Intervention group: received 1 unit of pearl vi

Eligibility

Sex/Gender

All

Age

16 Years to No maximum

Inclusion criteria

Inclusion criteria: moderate to severe asthma treated with inhaled corticosteroid (ICS) vitamin D deficiency No systemic disease No diabetes No infectious disease No liver disease No heart disease No kidney disease

Exclusion criteria

Exclusion criteria: patient expired patient who do not use his drug add new systemic disease change of treatment Patients taking antioxidant drugs Use of any medication that affects the mitochondrial system and antioxidant storage

Design outcomes

Primary

Measure	Time frame
Serum levels of antioxidants in the blood serum of patients. Timepoint: Measurement of serum antioxidant levels at the beginning of the study and 3 months after starting vitamin D intake. Method of measurement: Use of thiobarbituric acid method.;Serum levels of interleukin 10 in the blood serum of patients. Timepoint: Measurement of serum interleukin level 10 at the beginning of the study and 3 months after starting vitamin D intake. Method of measurement: Using the commercial kit by ELISA method.	—

Measure

Time frame

Serum levels of antioxidants in the blood serum of patients. Timepoint: Measurement of serum antioxidant levels at the beginning of the study and 3 months after starting vitamin D intake. Method of measurement: Use of thiobarbituric acid method.;Serum levels of interleukin 10 in the blood serum of patients. Timepoint: Measurement of serum interleukin level 10 at the beginning of the study and 3 months after starting vitamin D intake. Method of measurement: Using the commercial kit by ELISA method.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactZabihullah Mohaghegh

Birjand University of Medical Sciences

oabstudent@gmail.com+98 56 3232 3232

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026