Caffeine Dose and Autonomic Recovery

Effect of caffeine dose on heart rate variability, rate pressure product and some fatigue indexes after endurance exercise in trained men

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190720044283N4

Enrollment

Registered

2021-10-27

Start date

2021-09-26

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recovery of indicators of the autonomic nervous system.

Interventions

Intervention 1: Intervention group: Dose of 6 mg/kg of caffeine and endurance activity. Intervention 2: Intervention group: Dose of 9 mg/kg of caffeine and endurance activity. Intervention 3: Control

Eligibility

Sex/Gender

Male

Age

18 Years to 22 Years

Inclusion criteria

Inclusion criteria: Subjects have exercised regularly (three sessions per week or more) over the past two years None of the subjects used supplements or ergogenic aids. No use of anabolic steroids or central nervous system stimulants in the last two years No caffeine intake of more than 300 mg per day No history of cardiovascular and metabolic diseases No history of alcohol and tobacco use Optimal body composition and physical health

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Heart rate variability. Timepoint: 15 minutes after attending the laboratory (before breakfast), 35 minutes after supplementation, immediately and at 1, 2, 3, 5, 10, 20, 40, and 60 minutes after exercise. Method of measurement: Heart rate monitor (Polar-H10).;Systolic and diastolic blood pressure. Timepoint: 15 minutes after attending the laboratory (before breakfast), 35 minutes after supplementation, immediately and at 1, 2, 3, 5, 10, 20, 40, and 60 minutes after exercise. Method of measurement: hand barometer (Zenith, ZTH-5001, Switzerland).;Rate pressure product. Timepoint: At all points when heart rate and blood pressure will also be measured. Method of measurement: It is calculated by multiplying systolic blood pressure and heart rate.;Rate of Perceived Exertion (RPE). Timepoint: Immediately after exercise. Method of measurement: Borg scale (6-20).;Muscle Pain. Timepoint: Immediately after exercise until one hour after exercise. Method of measurement: Visual Analogue Scale (VAS).	—

Measure

Time frame

Heart rate variability. Timepoint: 15 minutes after attending the laboratory (before breakfast), 35 minutes after supplementation, immediately and at 1, 2, 3, 5, 10, 20, 40, and 60 minutes after exercise. Method of measurement: Heart rate monitor (Polar-H10).;Systolic and diastolic blood pressure. Timepoint: 15 minutes after attending the laboratory (before breakfast), 35 minutes after supplementation, immediately and at 1, 2, 3, 5, 10, 20, 40, and 60 minutes after exercise. Method of measurement: hand barometer (Zenith, ZTH-5001, Switzerland).;Rate pressure product. Timepoint: At all points when heart rate and blood pressure will also be measured. Method of measurement: It is calculated by multiplying systolic blood pressure and heart rate.;Rate of Perceived Exertion (RPE). Timepoint: Immediately after exercise. Method of measurement: Borg scale (6-20).;Muscle Pain. Timepoint: Immediately after exercise until one hour after exercise. Method of measurement: Visual Analogue Scale (VAS).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Javad Mehrabani

Faculty of Physical Education and Sports Sciences, University of Guilan

mehrabanij@guilan.ac.ir+98 911 230 9074

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026