Goal directed fluid therapy in spine surgery

Effects of goal-directed fluid therapy using LiDCOrapid system in postoperative outcomes and comparison with standard fluid therapy for patients undergoing spine surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190719044274N1

Enrollment

Registered

2019-09-28

Start date

2019-10-11

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with spine surgery due to Spinal canal stenosis, spondylopathies and etc with past medical history of Hypertension or Diabetes mellitus, Ischemic heart disease, Chronic obstructive pulmonary disease. Spondylosis

Interventions

Intervention 1: Intervention group: Fluid therapy based on Hemodynamic Monitoring such as Stroke Volume Variation, Cardiac Output, Systemic Vascular Resistance and etc given by LidcoRapid Hemodynamic

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: operations longer than 2 hours Ischemic heart disease Chronic obstructive pulmonary disease

Exclusion criteria

Exclusion criteria: Patient refusal Irregular heart rhythm

Design outcomes

Primary

Measure	Time frame
Base excess. Timepoint: Before intervention and 1, 2, 3 hours after intervention. Method of measurement: Arterial blood gas.;Days of hospital stay. Timepoint: ?Days of hospital stay after surgery. Method of measurement: Reading the files and visiting patients.;Days of Intensive Care Unit stay. Timepoint: Days of Intensive Care Unit stay after surgery. Method of measurement: Reading the files and visiting patients.;Postoperative nausea and vomiting. Timepoint: Nausea and vomiting after 12, 24 and 36 hours after surgery. Method of measurement: History Taking.;Pulmonary edema. Timepoint: Until 24 hours after surgery. Method of measurement: Chest Radiography and Physical examination.;Serum Transfusion. Timepoint: During Surgery. Method of measurement: Measurement of Serum given during surgey.;Oral intake Tolerance. Timepoint: 24 hours after surgery. Method of measurement: History taking.	—

Measure

Time frame

Base excess. Timepoint: Before intervention and 1, 2, 3 hours after intervention. Method of measurement: Arterial blood gas.;Days of hospital stay. Timepoint: ?Days of hospital stay after surgery. Method of measurement: Reading the files and visiting patients.;Days of Intensive Care Unit stay. Timepoint: Days of Intensive Care Unit stay after surgery. Method of measurement: Reading the files and visiting patients.;Postoperative nausea and vomiting. Timepoint: Nausea and vomiting after 12, 24 and 36 hours after surgery. Method of measurement: History Taking.;Pulmonary edema. Timepoint: Until 24 hours after surgery. Method of measurement: Chest Radiography and Physical examination.;Serum Transfusion. Timepoint: During Surgery. Method of measurement: Measurement of Serum given during surgey.;Oral intake Tolerance. Timepoint: 24 hours after surgery. Method of measurement: History taking.

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Secondary

Measure	Time frame
Acute Respiratory Distress Syndrome. Timepoint: 48 hours after surgery. Method of measurement: Chest Radiography, Blood gas analysis.;Pneumonia. Timepoint: 48 hours after surgery. Method of measurement: Clinical manifestation and Chest radiography.;Myocardial infarction. Timepoint: 48 hours after surgery. Method of measurement: Lab tests and Electrocardiography.;Hospital readmission. Timepoint: 30 days after discharge. Method of measurement: Postoperative evaluation.;Urinary Tract Infection. Timepoint: 48 hours after surgery. Method of measurement: Clinical manifestation, Urine analysis.	—

Measure

Time frame

Acute Respiratory Distress Syndrome. Timepoint: 48 hours after surgery. Method of measurement: Chest Radiography, Blood gas analysis.;Pneumonia. Timepoint: 48 hours after surgery. Method of measurement: Clinical manifestation and Chest radiography.;Myocardial infarction. Timepoint: 48 hours after surgery. Method of measurement: Lab tests and Electrocardiography.;Hospital readmission. Timepoint: 30 days after discharge. Method of measurement: Postoperative evaluation.;Urinary Tract Infection. Timepoint: 48 hours after surgery. Method of measurement: Clinical manifestation, Urine analysis.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Reza shariat Moharari

Tehran University of Medical Sciences

Moharari@tums.ac.ir+98 21 8889 6696

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026