effect of vitamin E on the prevention of acute renal injury in patients with leukemia

The effect of vitamin E on the prevention of acute renal injury in patients with leukemia receiving vincristine

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190717044255N7

Enrollment

Registered

2023-02-25

Start date

2023-03-25

Completion date

Unknown

Last updated

2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Leukemia. Lymphoid leukemia

Interventions

Intervention 1: Control group: In the control group, 18 patients received routine treatment with vincristine (Richter-Hungary) every week intravenously at a dose of 0.05 mg/kg for one month. During th

Eligibility

Sex/Gender

All

Age

3 Years to 18 Years

Inclusion criteria

Inclusion criteria: Leukemia patients taking vincristine Age 3 to 18 years

Exclusion criteria

Exclusion criteria: Suffering from chronic kidney disease Allergy to vitamin E medicine

Design outcomes

Primary

Measure	Time frame
Glomerular filtration rate (GFR). Timepoint: At entry into the study, 48 hours later, one week and one month after the start of treatment. Method of measurement: Creatinine clearance formula.	—

Secondary

Measure	Time frame
Serum creatinine level. Timepoint: At entry into the study, 48 hours later, one week and one month after the start of treatment. Method of measurement: Laboratory measurement of serum creatinine level.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Toghra

Arak University of Medical Sciences

Dralirezatoghra7273@gmail.com0098863134905

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026