obesity. Overweight and obesity
Conditions
Interventions
Intervention 1: Intervention group: fasting mimicking diet will be administered during the first 5 days of a month (In total, 2 five-days cycles for 2 months). Fasting mimicking diet is a plant-based
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: healthy women aged 18-50 years BMI ranged from 30 to 35 not to use any tobacco regular menstrual cycle not to have symptoms of hyperandrogenism or PCOS not to use contraceptive drugs negative pregnancy test not having metabolic disorder affecting gluconeogenesis not having medical history of heart diseases not having considerable food allergies weight change less than 3 kg in the last 3 months not having psychotic disorder affecting the patients' adherence
Exclusion criteria
Exclusion criteria: not to have adherence to the diet unwilling to continue the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body weight. Timepoint: Body weight will be measured just before the inclusion in the trial and at the end of the intervention (after 2 months). Method of measurement: digital scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body fat mass. Timepoint: Body fat mass will be measured just before the inclusion in the trial and at the end of the intervention (after 2 months). Method of measurement: Body composition analyzer.;Fat free mass. Timepoint: Fat free mass will be measured just before the inclusion in the trial and at the end of the intervention (after 2 months). Method of measurement: Body composition analyzer.;Serum glucose. Timepoint: Serum glucose will be measured just before the inclusion in the trial and at the end of the intervention (after 2 months). Method of measurement: enzymatic methods.;Serum insulin. Timepoint: Serum glucose will be measured just before the inclusion in the trial and at the end of the intervention (after 2 months). Method of measurement: ELISA.;Ghrelin. Timepoint: Serum ghrelin will be measured just before the inclusion in the trial and at the end of the intervention (after 2 months). Method of measurement: ELISA.;Leptin. Timepoint: Serum leptin will be measured just before the inclusion in the trial and at the end of the intervention (after 2 months). Method of measurement: ELISA.;Neuropeptide Y. Timepoint: Serum neuropeptide Y will be measured just before the inclusion in the trial and at the end of the intervention (after 2 months). Method of measurement: ELISA.;Waist circumference. Timepoint: Waist circumference will be measured just before the inclusion in the trial and at the end of the intervention (after 2 months). Method of measurement: Meter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehdi Sadeghian
Ahvaz University of Medical Sciences
Outcome results
None listed