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The effect of bupivacaine with adrenaline in comparison with bupivacaine with neostigmine in induction of spinal anesthesia in TURP surgery

Evaluation the effect of bupivacaine with adrenaline in comparison with bupivacaine with neostigmine in induction of spinal anesthesia in TURP surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190715044224N1
Enrollment
100
Registered
2019-08-16
Start date
2019-08-23
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign prostate Hyperplasia. Enlarged prostate

Interventions

Intervention 1: Intervention group: The first group of will receive bupivacaine (ASTrazeneca Company) at a dose of 5 mg with adrenaline (Daro Pakhsh Company) at a dose of 0.1 to 0.2 cc will be adminis

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: Indication for TURP surgery BMI 25 to 30 Satisfaction to perform TURP surgery 40 to 75 years old

Exclusion criteria

Exclusion criteria: Patient dissatisfaction Brain lesions Infective problems, such as cellulitis at the injection site Motion sickness Thrombocytopenia Sepsis Taking anti-coagulant medication Coagulation disorders Taking NSAID Taking androgen drugs Liver cirrhosis Contraindications for receiving adrenaline and neostigmine Mitral valve stenosis and aortic valve stenosis low blood pressure

Design outcomes

Secondary

MeasureTime frame
Systolic and diastolic blood pressure. Timepoint: 15 minutes after injection and 6-12 hours after surgery. Method of measurement: Manometer device from AND Company model UA - 767JP.

Primary

MeasureTime frame
Pain during and after TURP surgery. Timepoint: 15 minutes after injection and 6-12 hours after surgery. Method of measurement: Visual Analogue Scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactYousef Kolookhi

Islamic Azad University

dryousefkolookhianestezi@gmail.com+98 23 3224 2487

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026