The effect of different mouthwashes on oral hygiene of patients using ventilator

Comparing the efficacy of Matricaria chamomilla, Achillea millefolium, and chlorhexidine gluconate mouthwashes on dental plaque and oral mucosal lesions of patients using ventilator in the intensive care unit

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190714044197N1

Enrollment

Registered

2019-08-04

Start date

2019-07-23

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: oral mucosal lesions. Condition 2: dental plaque. Unspecified lesions of oral mucosa Dental caries, unspecified

Interventions

Intervention 1: Intervention group 1 (Matricaria chamomilla): Matricaria chamomilla extract at a concentration of 10 percent (made by Adonis Gol Darou Company) will be administered three times daily w

Eligibility

Sex/Gender

All

Age

15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Informed consent provided by the patient or guardian for participation Age between 15 and 65 years Less than 6 hours passed from the patient's admission in the intensive care unit Having an oral tube Having at least 12 natural teeth and not having more than 6 dentures

Exclusion criteria

Exclusion criteria: Diabetes Immune system disorders Traumatic oral injuries Taking anti-coagulant drugs

Design outcomes

Primary

Measure	Time frame
Oral mucosal lesions. Timepoint: Before the intervention, the second and fifth days after the intervention. Method of measurement: Beck Oral Assessment Scale.;Dental plaque. Timepoint: Before the intervention, the second and fifth days after the intervention. Method of measurement: Mucosal-plaque score index.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Sabzeh Kar

Birjand University of Medical Sciences

fsabzehkar@bums.ac.ir+98 56 3245 4252

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026