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Therapeutic effects of Dosin (Nigella sativa and Honey) vaginal Cream on Candida Vulvovaginitis

Comparison of the therapeutic effect of Honey and Nigella sativa (Dosin) vaginal cream and Clotrimazole vaginal cream in treatment Candida Vulvovaginitis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190711044176N1
Enrollment
84
Registered
2019-07-26
Start date
2019-07-23
Completion date
Unknown
Last updated
2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Candida VulvoVaginitis. Candidiasis of vulva and vagina (N77.1*)

Interventions

Intervention 1: Intervention group: Intervention group: honey and Nigella Sativa"Dosin" vaginal cream each night as an applicator inside the vagina for 7 nights. Intervention 2: Control group: Contro

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 49 Years

Inclusion criteria

Inclusion criteria: Women were married and aged between 18-49 years old Not being pregnancy Not being lactation Not Having Allergy to Honey or Nigella Sativa or Clotrimazole Not being period Not using vaginal cream and vaginal doush and for last 48 hours before the study Not Having of history of diabetes and deficiency of immune system Not Having recurrent Candida vaginitis (4 or more Candida vaginitis in a year) Not Having of history of curettage, Hysterosalpingography and uterine surgery in the last two weeks No history of receiving blood or chemotherapy in a recent month Having of signs and symptoms of Candida vaginitis, positive direct smear and culther of vaginal discharge

Exclusion criteria

Exclusion criteria: Not Agreeing to Participate in the Study The use of antibiotics to treat non-vaginitis systemic infections during treatment Participation at another trial Pregnancy in the study time table

Design outcomes

Primary

MeasureTime frame
Symptoms and signs of Candida Vulvovaginitis. Timepoint: Before intervention, 6-10 day after treatment. Method of measurement: Questionnaire,Microscopic evaluation,Secretion culture,Measurements Of Ph.

Secondary

MeasureTime frame
Improve Of Candida Vulvovaginitis. Timepoint: 6-10 Day After Treatment. Method of measurement: Questionnaire, culther.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoumeh Norouzi

Tehran University of Medical Sciences

norouzi7378@gmail.com+98 21 6105 4215

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 11, 2026