The effect of Dexmedetomidine? Ondansetrone? Pethidine on tremor after abdominal surgery

The prophylactic effect of intravenous injection of Dexmedetomidine? Ondansetrone? Pethidine on tremor after abdominal surgery under the general anesthesia and comparisone with control group

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190708044155N1

Enrollment

128

Registered

2019-08-25

Start date

2019-06-30

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Teremor rate after surgery. Tremor, unspecified

Interventions

Intervention 1: Intervention 1: In group D 0.5mg / kg dexmedetomidine - injected intravenously 1 time after the last wound is closed. Intervention 2: Intervention group 2: In group P 0.5mg / kg pethid

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Men and women with ASA 1 and 2 Candidate for abdominal surgery under general anesthesia 18 to 60 years old

Exclusion criteria

Exclusion criteria: History of Vasoactive Drugs, Opioids, TCA, MAOI Nerve and muscle disease Thyroid disease Fever Pregnancy Obesity BMI> 27 Cardiovascular, Respiratory, Endocrine, Neurological diseases Sensitivity to Pethidine, Ondansetrone, Ketamine

Design outcomes

Primary

Measure	Time frame
Tremor rate after surgery. Timepoint: For the first 15 minutes continuously and then every 15 minutes to 1 hour. Method of measurement: Crassly and Mahajan.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahsa Heydari

Esfahan University of Medical Sciences

mahsaheydari.mahsa@gmail.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026