Irritable Bowel Syndrome. Irritable bowel syndrome
Conditions
Interventions
Intervention 1: Intervention group: Propolis extract at a dose of 500 mg per day for six weeks, taking 2 tablets daily. Intervention 2: Control group: Placebo at a dose of 500 mg per day for six conse
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients diagnose irritable bowel syndrome with Rome IV criteria Filling out the written consent form Not having allergy to bee products
Exclusion criteria
Exclusion criteria: Pregnant or lactating women Cases of malignancy or other chronic digestive diseases such as inflammatory bowel disease and celiac disease Regular use of drugs that modify gastrointestinal movements such as metoclopramide, cisapride, narcotics, diphenoxylate, etc. Regular use of laxatives History of major surgery in the digestive system (including Billroth's operating, having any Ostomy and resection of any part of the digestive tract). Following diet plans Individuals with daily and regular use of Prebiotic/ probiotic compounds Consumption antibiotics People who use psychotherapeutic drugs, including depression and anxiety.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of Irritable bowel syndrome. Timepoint: At the beginning of the study and the sixth week of the intervention. Method of measurement: IBS Severity Index(IBSSI). | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life in Patients with Irritable Bowel Syndrome. Timepoint: At the beginning of the study and the sixth week of the intervention. Method of measurement: Irritable Bowel Syndrome Quality of Life questionnaire (IBS-QOL).;Food intake in Patients with Irritable Bowel Syndrome. Timepoint: At the beginning of the study and the sixth week of the intervention. Method of measurement: 3-Day Food Intake Record. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahsa Miryan
Tabriz University of Medical Sciences
Outcome results
None listed