Effect of transcranial direct current stimulation and high definition stimulation on restless leg syndrome

Comparison of the effect of transcranial direct current stimulation (tDCS) and high definition stimulation (HD-tDCS) on cognitive-psychological symptoms in adults with restless leg syndrome (RLS)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190708044138N1

Enrollment

Registered

2020-05-07

Start date

2019-07-23

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

restless legs syndrome. Restless legs syndrome

Interventions

Intervention 1: The first intervention group received transcranial direct current stimulation (HD-tDCS) at 4 mA (positive or anode stimulation) over 10 consecutive sessions (25 minutes per session). I

Eligibility

Sex/Gender

All

Age

18 Years to 75 Months

Inclusion criteria

Inclusion criteria: Diagnosis of restless legs syndrome by a psychiatrist or psychologist Gaining moderate to high score in severity of the syndrome (scores of 5 to 12) in the international restless legs syndrome questionnaire Rejecting differential diagnosis of neuro-motor disorder by a neurologist and absence of neurological disorder Aged between 18 to 75 years Not suffering from cardiovascular disease, kidney disease and diabetes (getting information by asking from participants and get help from a physician) Not Smoking and not taking painkillers, sedatives and hypnotics Non-pregnancy in women

Exclusion criteria

Exclusion criteria: Dissatisfaction to participate in the research Having a type of motor or cognitive disabilities that interferes working with computer Receiving simultaneous psychiatric treatment or other psychotherapies to relieve RLS symptoms History of seizure disorders in individuals, having a pacemaker, having a metal object in the head and neck or any other obstacle to do electrical stimulation

Design outcomes

Primary

Measure	Time frame
Cognitive Symptoms. Timepoint: Cognitive Symptoms was measured at the beginning of the study (before the intervention), after the last treatment session, and 30 days (one month) after the last treatment session. Method of measurement: The Integrated Visual and Auditory (IVA-2).;Depression. Timepoint: Depression was measured at the beginning of the study (before the intervention), after the last treatment session, and 30 days (one month) after the last treatment session. Method of measurement: beck depression inventory (BDI-II).;Severity of Restless Legs Syndrome. Timepoint: Severity of Restless Legs Syndrome was measured at the beginning of the study (before the intervention), after the last treatment session, and 30 days (one month) after the last treatment session. Method of measurement: International Restless Legs Syndrome Questionnaire.	—

Measure

Time frame

Cognitive Symptoms. Timepoint: Cognitive Symptoms was measured at the beginning of the study (before the intervention), after the last treatment session, and 30 days (one month) after the last treatment session. Method of measurement: The Integrated Visual and Auditory (IVA-2).;Depression. Timepoint: Depression was measured at the beginning of the study (before the intervention), after the last treatment session, and 30 days (one month) after the last treatment session. Method of measurement: beck depression inventory (BDI-II).;Severity of Restless Legs Syndrome. Timepoint: Severity of Restless Legs Syndrome was measured at the beginning of the study (before the intervention), after the last treatment session, and 30 days (one month) after the last treatment session. Method of measurement: International Restless Legs Syndrome Questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hossein Sorbi

Urmia University

sorbih@gmail.com+98 44 3275 2741

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026