cancer. Carcinoma in situ of other and unspecified digestive organs
Conditions
Interventions
Intervention 1: Intervention group: Intervention group (A)Receives 10% zinc chloride solution 2 times every 8 hours and 10 cc each time.Patients rinse for 2 minutes.The time interval between the two s
Sponsors
Hamedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: • Patients with cancer aged 18-65 years • Stage I and II of Cancer • Under chemotherapy • With no oral ulcer • To be able to carry out a mouthwash • Having a normal level of white blood cells and platelets • Not using another medication to prevent and treat oral mucositis • Not being in pregnancy and lactation time • Not receiving chemotherapy and radiotherapy simultaneously • No other physical and mental disorders • Insensitivity to zinc chloride and sodium bicarbonate • Receiving at least one drug from the category of commonly used chemotherapy drugs • Not receiving chemotherapy drugs which increase mucositis, such as actinomycin and ...
Exclusion criteria
Exclusion criteria: • Absence in at least one session of determined days for treatment follow-up • Hypersensitivity to zinc chloride and sodium bicarbonate • Extensive disability and weakness of the patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treatment of oral mucositis. Timepoint: 1 day before the intervention and 1, 4, 7 and 14 days after the intervention. Method of measurement: Visual Analogue Scale, Oral mucositis index, World Health Organization criteria for grading of oral mucositis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFateme Mohammadi
Hamedan University of Medical Sciences
Outcome results
None listed