The effect of diet and regular aerobic activity on fatty liver

The effect of high-fiber diet along with regular aerobic activity on changes in liver indices and triglyceride levels in non-alcoholic fatty liver patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190702044080N2

Enrollment

Registered

2026-01-07

Start date

2024-05-21

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nonalcoholic fatty liver disease.

Interventions

Intervention 1: Intervention group: High-fiber diet group: Subjects in this group received a high-fiber diet (30 grams of fiber) daily for 8 weeks. Intervention 2: Intervention group: Combination (hig

Eligibility

Sex/Gender

Female

Age

25 Years to 53 Years

Inclusion criteria

Inclusion criteria: - Willingness to cooperate - Non-alcoholic fatty liver disease and confirmation of its diagnosis by a specialist doctor and laboratory and ultrasound evidence - Age over 20 years - Body mass index over 25

Exclusion criteria

Exclusion criteria: Unwillingness to cooperate Pregnancy, breastfeeding and menopause History of cardiovascular diseases, diabetes, hyperthyroidism and hypothyroidism, infectious diseases, cirrhosis, kidney failure and cancer Smoking, alcohol and tobacco use Consumption of prebiotics in the past 3 months Regular exercise in the past 6 months Following any special diet in the past 1 month Use of any medication and food supplement in the past 1 month

Design outcomes

Primary

Measure	Time frame
Triglycerides (TG) are a type of fat found in the blood that are essential for health, but high levels can increase the risk of heart disease. Timepoint: 24 hours before the first training session and 48 hours after the last training session. Method of measurement: Colorimetric method (Parsamon, Tehran, Iran).;Total cholesterol (TC) is the sum of all cholesterols in the blood. Cholesterol is a type of fat that plays important roles in the body, but too much of it can increase the risk of cardiovascular disease. Timepoint: 24 hours before the first training session and 48 hours after the last training session. Method of measurement: Colorimetric method (Parsamon, Tehran, Iran).;High-density lipoprotein (HDL) is known as “good cholesterol” because it helps remove excess cholesterol from the blood and prevents fat from building up in the arteries. Timepoint: 24 hours before the first training session and 48 hours after the last training session. Method of measurement: Colorimetric method (Parsamon, Tehran, Iran).;Low-density lipoprotein (LDL) is known as “bad cholesterol” because it deposits in the walls of arteries and can lead to the formation of fatty plaques. Timepoint: 24 hours before the first training session and 48 hours after the last training session. Method of measurement: by using the Friedewald formula.;Aspartate aminotransferase (AST) is an enzyme found in the liver, heart, muscles, and other organs. Elevated levels of AST in the blood can indicate liver damage or other health conditions. Timepoint: 24 hours before the first training session and 48 hours after the last training session. Method of measurement: ELISA laboratory kits.;An enzyme found primarily in the liver and to a lesser extent in other tissues such as heart muscle, kidneys, pancreas, and skeletal muscle. ALT plays a role in converting amino acids into other molecules that can be used by cells for energy and growth. Timepoint: 24 hours before the first training session and 48 hours after th	—

Measure

Time frame

Triglycerides (TG) are a type of fat found in the blood that are essential for health, but high levels can increase the risk of heart disease. Timepoint: 24 hours before the first training session and 48 hours after the last training session. Method of measurement: Colorimetric method (Parsamon, Tehran, Iran).;Total cholesterol (TC) is the sum of all cholesterols in the blood. Cholesterol is a type of fat that plays important roles in the body, but too much of it can increase the risk of cardiovascular disease. Timepoint: 24 hours before the first training session and 48 hours after the last training session. Method of measurement: Colorimetric method (Parsamon, Tehran, Iran).;High-density lipoprotein (HDL) is known as “good cholesterol” because it helps remove excess cholesterol from the blood and prevents fat from building up in the arteries. Timepoint: 24 hours before the first training session and 48 hours after the last training session. Method of measurement: Colorimetric method (Parsamon, Tehran, Iran).;Low-density lipoprotein (LDL) is known as “bad cholesterol” because it deposits in the walls of arteries and can lead to the formation of fatty plaques. Timepoint: 24 hours before the first training session and 48 hours after the last training session. Method of measurement: by using the Friedewald formula.;Aspartate aminotransferase (AST) is an enzyme found in the liver, heart, muscles, and other organs. Elevated levels of AST in the blood can indicate liver damage or other health conditions. Timepoint: 24 hours before the first training session and 48 hours after the last training session. Method of measurement: ELISA laboratory kits.;An enzyme found primarily in the liver and to a lesser extent in other tissues such as heart muscle, kidneys, pancreas, and skeletal muscle. ALT plays a role in converting amino acids into other molecules that can be used by cells for energy and growth. Timepoint: 24 hours before the first training session and 48 hours after th

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAboutaleb Bagheri

Islamic Azad University

talebbagheri@iau.ir+98 61 4255 5298

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026