Chronic Obstructive Pulmonary Disease. Chronic obstructive pulmonary disease, unspecified
Conditions
Interventions
Intervention group: The intervention group will include 5 COPD patients at Stage 3 & 4. First, Informed consent form will be provided for Participants and will be completed by Patient or in the case o
Cardio Pulmonary Exercise Testing and the health screening tests before activity based on the American College of Sports Medicine (ACSM) guidelines, will be taken with supervision of Sports medicine p
Including the interval aerobic exercise and inspiratory muscle training (IMT). 24 to 48 hours after the end of the Exercise intervention, the above mentioned tests will be carried out as a post-test t
will be performed as walking or cycling on a treadmill or cycle ergometer. during this period
Heart rate and ECG, Arterial oxygen saturation percentage (SaO2), and blood pressure will be monitored using the Vital signs monitor and Pulse Oximeter. the intensity of the aerobic exercise program:
Third and fourth weeks,
Sponsors
Shiraz University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Chronic Obstructive Pulmonary Disease Stage 3 and 4
Exclusion criteria
Exclusion criteria: Uncontrolled cardiovascular disease ( decompensated CHF, uncontrolled arrhythmia, myocardial infarction or unstable angina during recent 6 weeks) uncontrolled hypertension (systolic blood pressure more than 180 mm-Hg / diastolic blood pressure more than 110 mm Hg) any musculo-skeletal disease and Motor restriction which preclude exercise program moderate to severe COPD exacerbation leading to hospital admission during recent 6 weeks performing regular exercise or participation in cardiac or pulmonary rehabilitation during recent 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FEV1 (Forced Expiratory Volume in the first Second): is the volume of air that can forcibly be blown out in the first second, after full inspiration. In another words, this indicator shows the volume of expiratory air in the first second of vital capacity. (Vital Capacity; The maximum volume of air that can be blown out after a very deep inspiration). Timepoint: Before and after the 6th and final week of the intervention, as a Pulmonary Function Test (PFT). Method of measurement: Using spirometry, measured in Liters. | — |
Secondary
| Measure | Time frame |
|---|---|
| FVC (Forced vital capacity): is the volume of air that can be blown out of the lungs with more intensity and maximum power, after full inspiration. Timepoint: Before and after the 6th and final week of the intervention, as a Pulmonary Function Test (PFT). Method of measurement: Using spirometry, measured in Liters.;TLC (Total lung capacity): is the maximum volume of air that can be placed in the lungs and is about 5800 ml. Timepoint: Before and after the 6th and final week of the intervention, as a Pulmonary Function Test (PFT). Method of measurement: Using Plethysmograph or "body box", measured in Liters.;RV (Residual volume): the volume of air remaining in the lungs at the end of a very deep exhalation. Timepoint: Before and after the 6th and final week of the intervention, as a Pulmonary Function Test (PFT). Method of measurement: Using Plethysmograph or "body box", measured in Liters.;FRC (Functional Residual Capacity): The volume of air that remains in the lungs after a normal exhalation, when the lungs and chest are resting. Timepoint: Before and after the 6th and final week of the intervention, as a Pulmonary Function Test (PFT). Method of measurement: Using Plethysmograph or "body box" or Indirect spirometry with helium dilution method, measured in Liters.;HRR index ( Heart rate recovery ): Is the rate of return heart rate to rest mode In the first minute after stopping exercise, Which reflects the reactivation of the parasympathetic system, and a delay in its decline indicates impaired cardiac function. Timepoint: Before and after the 6th and final week of the intervention; 1 minute after the end of the exercise test. Method of measurement: Usin the Electrocardiography or Polar™ Heart rate sensor.;RPP index (Rate Pressure Product): Indicates the amount of internal Cardiac muscle work and it's used to showing the workload and oxygen consumption of myocardium, and obtained by multiplying the systolic blood pressure in the heart rate. [RPP = SBP × HR/1000]. Ti | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mohammad Javad Fallahi
Shiraz University of Medical Sciences
Outcome results
None listed