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The effect of simvastatin on reducing tooth pain

Local clinical effect of simvastatin tablets on pain after maxillary premolar tooth extraction in patients recommended for orthodontic treatment

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190701044070N1
Enrollment
10
Registered
2019-07-06
Start date
2018-10-28
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tooth pain.

Interventions

Intervention group: The first premolar was the one used with simvastatin.

Sponsors

Sari University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: The orthodontic order to extract of each 2 maxillary premolars for future orthodontic treatment

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The amount of pain. Timepoint: Before, 30 minutes later, 6 hours, 12 hours and 24 hours after surgery. Method of measurement: The VAS is a 10-cm linear scale that is graded from zero to ten and is zero in the no-pain sense and ten most severe pain. After considering the line, the patient determines the amount of pain on the line, and then the pain is calculated based on millimeters from the origin of zero.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Reza Mofidian

Sari University of Medical Sciences

reza_mofidian@yahoo.com+98 11 3304 4001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026