Ulcerative Colitis. Ulcerative colitis
Conditions
Interventions
Intervention 1: Intervention group: The intervention group is prescribed 2 grams of mesalazine tablets and saffron solution as a solution of 300 mg of saffron in 50 cc of water, daily for 4 weeks and
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who's disease is diagnosed recently or recent relapce Patients who can tolerate enema
Exclusion criteria
Exclusion criteria: Patients with good controlled disease Patients who can't tolerate enema Patients with associated disease: Crohn, Intermediate colitis, CMV, Pseudomembrano colitis, Heart failure, Renal failure, PSC
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease activity based on Mayo score. Timepoint: Assessment of disease activity at the beginning of the study and 28 days after the start of saffron enema solution. Method of measurement: Mayo Score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequent defecation. Timepoint: Evaluation of stool frequency at the beginning of the study and 28 days after starting saffron enema solution. Method of measurement: Mayo Score.;Rectal bleeding. Timepoint: Evaluation of rectal bleeding at the beginning of the study and 28 days after starting saffron enema solution. Method of measurement: Mayo score.;Endoscopic findings. Timepoint: Evaluation of endoscopic findings at the beginning of the study and 28 days after starting saffron enema. Method of measurement: Mayo score. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactManouchehr Khoshbaten
Tabriz University of Medical Sciences
Outcome results
None listed