Effects of ANSIL in the treatment of anal fissures

comparing the effect of the Ansil gel with placebo on the treatment of acute Anal fissure

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190701044062N10

Enrollment

Registered

2022-02-19

Start date

2021-04-18

Completion date

Unknown

Last updated

2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute Anal fissure. Acute anal fissure

Interventions

Intervention 1: Intervention group:0/2% ?Ansil gel (Silver Nitrate) which is made using the nanoparticle mechanism at Tabriz University of Iran and is applied to the wound for two weeks, twice a day i

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 18 to 65 years old cases with Anal fissure symptoms and diagnosis of Anal fissure whithout emergency interventions based on physical examination Do not use any drug other than the drug under study and the placebo for treatment of Anal fissure during the study period

Exclusion criteria

Exclusion criteria: chronic Anal fissure lateral fissure the period of pregnancy or breastfeeding

Design outcomes

Primary

Measure	Time frame
Anal Fissure healing. Timepoint: at baseline and 2 week after the intervention. Method of measurement: physical examination and health history.	—

Secondary

Measure	Time frame
Anal itching. Timepoint: at baseline and 2 week after the intervention. Method of measurement: health history.;Anal bleeding. Timepoint: at baseline and 2 week after the intervention. Method of measurement: health history.;Anal pain at rest. Timepoint: at baseline and 2 week after the intervention. Method of measurement: ??? ??? ????.;Anal pain during defecation. Timepoint: at baseline and 2 week after the intervention. Method of measurement: health history.;Pulse sensation after defecation. Timepoint: at baseline and 2 week after the intervention. Method of measurement: health history.;Feeling of a mass around the anus. Timepoint: at baseline and 2 week after the intervention. Method of measurement: health history.;Bleeding of the fissure during the examination. Timepoint: at baseline and 2 week after the intervention. Method of measurement: physical examination.;Pain at the Fissure site during the examination. Timepoint: at baseline and 2 week after the intervention. Method of measurement: physical examination.	—

Measure

Time frame

Anal itching. Timepoint: at baseline and 2 week after the intervention. Method of measurement: health history.;Anal bleeding. Timepoint: at baseline and 2 week after the intervention. Method of measurement: health history.;Anal pain at rest. Timepoint: at baseline and 2 week after the intervention. Method of measurement: ??? ??? ????.;Anal pain during defecation. Timepoint: at baseline and 2 week after the intervention. Method of measurement: health history.;Pulse sensation after defecation. Timepoint: at baseline and 2 week after the intervention. Method of measurement: health history.;Feeling of a mass around the anus. Timepoint: at baseline and 2 week after the intervention. Method of measurement: health history.;Bleeding of the fissure during the examination. Timepoint: at baseline and 2 week after the intervention. Method of measurement: physical examination.;Pain at the Fissure site during the examination. Timepoint: at baseline and 2 week after the intervention. Method of measurement: physical examination.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactManouchehr Khoshbaten

Tabriz University of Medical Sciences

mkhoshbaten@yahoo.com+98 41 3337 2088

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026