Evaluation of Dexmedetomidine effect on mentally-disabled adults, candidate for dental treatment under general aneasthesia

Evaluation of administration of Dexmedetomidine on recovery conditions in mentally-disabled adults, candidate for dental treatment under general aneasthesia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190626044013N2

Enrollment

Registered

2021-04-16

Start date

2021-04-04

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mental disability. Unspecified intellectual disabilities

Interventions

Intervention 1: Intervention group:2 mcg/kg/hr dexmedetomidine will be administered via infusion until the end of general anesthesia. Intervention 2: Control group: 50% N2O / 50% O2 along with 100 mcg

Eligibility

Sex/Gender

All

Age

10 Years to 50 Years

Inclusion criteria

Inclusion criteria: mentally disabled without systemic diseases or physical disabilities need dental treatment under general aneasthesia

Exclusion criteria

Exclusion criteria: unwilling to participate in the study using tranquillizers, anticonvulsive, antidepressants, antipsychotic drugs allergic to soy or eggs hepatic diseases Morbidly obese (BMI=40)

Design outcomes

Primary

Measure	Time frame
Agitation in recovery. Timepoint: once. Method of measurement: Richmond Scale.	—

Secondary

Measure	Time frame
Heart rate. Timepoint: Once every 15 minutes during anesthesia. Method of measurement: pulsometer.;Anesthesia time. Timepoint: Once during anesthesia. Method of measurement: clock.;Analgesia need in recovery. Timepoint: Once during the patient's recovery. Method of measurement: recording.;Recovery time. Timepoint: Once during the patient's recovery. Method of measurement: clock.;Systolic blood pressure. Timepoint: Once every 15 minutes during anesthesia. Method of measurement: pressure cuff.	—

Measure

Time frame

Heart rate. Timepoint: Once every 15 minutes during anesthesia. Method of measurement: pulsometer.;Anesthesia time. Timepoint: Once during anesthesia. Method of measurement: clock.;Analgesia need in recovery. Timepoint: Once during the patient's recovery. Method of measurement: recording.;Recovery time. Timepoint: Once during the patient's recovery. Method of measurement: clock.;Systolic blood pressure. Timepoint: Once every 15 minutes during anesthesia. Method of measurement: pressure cuff.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Naser Kaviani

Esfahan University of Medical Sciences

kaviani@dnt.mui.ac.ir+98 31 3792 5558

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026