The Effect of Sertraline and L-Carnitine on Reducing Blood Pressure in Dialysis Patients

Comparison of sertraline and l-carnitine in treatment of dialysis induced hypotension in patient with ESRD and under dialysis

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190624043997N1

Enrollment

Registered

2019-08-08

Start date

2019-08-01

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypotention. Chronic kidney disease, unspecified

Interventions

Intervention 1: Intervention group: The first intervention group, consumes one dose of sertraline 50 mg per day for 4 weeks. Intervention 2: Intervention group: The second intervention group, consumes

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who undergo dialysis for at least 2 months and at least 50% of their dialysis sessions are associated with hypotension

Exclusion criteria

Exclusion criteria: 1. Use high flux filter 2. Use acetate solution 3. New use of blood pressure lowering medication

Design outcomes

Primary

Measure	Time frame
HYPOTENTION. Timepoint: Blood pressure of patients will be recorded before the start of the study in 3 times before dialysis, during and after dialysis (based on mmHg), and after 4 weeks of taking the medication, the blood pressure of the patients was repeated in 3 sessions of dialysis in the same way Will be measured again. Method of measurement: Mercury barometric.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSepideh Hajian

Qazvin University of Medical Sciences

dr.sepide_hajian@yahoo.com+98 28 3379 6020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026