Covid-19. Virus identified
Conditions
Interventions
Intervention 1: Intervention group: Patients with Covid-19 disease will receive 20 mg Isotretinoin twice daily along with the standard of care for 7 days. Intervention 2: Control group: Patients with
Sponsors
Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Positive covid-19 test During first 48 hours of symptoms
Exclusion criteria
Exclusion criteria: Underlying hematologic disease Underlying liver disease Known allergy to Isotretinoin Pregnancy/lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Cure. Timepoint: Seven and 14 days after treatment initiation. Method of measurement: Clinical and laboratory evaluations.;Virological cure. Timepoint: Day 7. Method of measurement: PCR.;ABG findings. Timepoint: Day 7. Method of measurement: Laboratory assessment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Radiological cure, organ dysfunction, death. Timepoint: Day 14. Method of measurement: Clinical and para-clinical data.;Organ dysfunction. Timepoint: Day 7. Method of measurement: Clinical and laboratory data.;Death. Timepoint: Day 28. Method of measurement: Observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactForoud Shahbazi
Kermanshah University of Medical Sciences
Outcome results
None listed