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Effect of potassium citrate consumption on the results of Transurethral Ureterolithotripsy

Studying the effect of potassium citrate consumption before lithotripsy on the results of Transurethral Uretero Lithotripsy (TUL): A clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190624043991N35
Enrollment
125
Registered
2025-11-03
Start date
2026-01-21
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney stones. Calculus of kidney

Interventions

Intervention 1: Intervention group: The group that consumes potassium citrate at a dose of 60 mEq per day, three times a day, from two weeks before stone crushing to one month after stone crushing. In

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Candidates for surgery of Transurethral Ureterolithotripsy Average age 18-75 who are willing to participate in the study

Exclusion criteria

Exclusion criteria: People with high urinary citrate levels. Have an acute urinary tract disease. Pregnancy. People with bleeding and coagulation disorders. People with distal ureteral obstruction with stones. People with drug sensitivity to potassium citrate.

Design outcomes

Primary

MeasureTime frame
The appearance of the stone is reported and recorded by the operator. Timepoint: After one and three months of lithotripsy, the patients' SFR and the presence of stone remnants are checked by ultrasound. Additionally, an ultrasound examination will be performed to assess the recurrence or non-recurrence of the stone after 6 months. Method of measurement: ultrasound.

Secondary

MeasureTime frame
To monitor changes in urinary citrate and pH levels, a 24-hour urine sample is collected 2 weeks before lithotripsy and after stopping potassium citrate. Timepoint: a 24-hour urine sample is collected 2 weeks before lithotripsy and after stopping potassium citrate. Method of measurement: Medical diagnostic laboratory.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Zahra Navi

Tehran University of Medical Sciences

shahrzadn951@gmail.com+98 21 6634 8560

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026