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effect of Finasteride on the encrustation of Double J

Investigating the effect of Finasteride on the encrustation of Double J stents in high-risk groups for Double-J encrustation: A Single-Blind Randomized Clinical Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190624043991N34
Enrollment
150
Registered
2025-10-02
Start date
2026-02-19
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High-risk groups for developing double-G. Acute nephritic syndrome

Interventions

Intervention 1: Intervention group: 75 people will be assigned to the double-jejunal treatment group, along with oral finasteride and standard antibiotic therapy. The finasteride medication used in th

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Men over the age of 18. Candidates for Double-J stents. Having informed consent.

Exclusion criteria

Exclusion criteria: Having liver diseases and disorders.

Design outcomes

Primary

MeasureTime frame
Assessing the risk of crusting in patients with double-jewel implants. Timepoint: The Double G stent is removed 4-6 weeks after placement. After removal of the Double G, its crusting grade is visually determined using the FECal grading system from Grade I to Grade V. Method of measurement: crusting grade is visually determined using the FECal grading system from Grade I to Grade V.

Secondary

MeasureTime frame
The results of 24-hour urine analysis. Timepoint: The results of the 24-hour urine test are recorded on the day of the operation and insertion of the double-jeweler, and again on the day of removal of the double-jeweler. Method of measurement: Medical diagnosis laboratory.;Pain level based on VAS. Timepoint: On the first day after surgery, the 14th day after surgery, and the day of discharge from the hospital (before surgery). Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Zahra Navi

Tehran University of Medical Sciences

shahrzadn951@gmail.com+98 21 6634 8593

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026