kidney stone disease. Acute nephritic syndrome
Conditions
Interventions
Intervention 1: 80 patients entered the study by filling out an informed consent form. They received the probiotic supplement BioFlora, which includes probiotic bacteria (lactobacillus acidophilus, bi
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Adult patients aged 18 to 70. The patients require percutaneous nephrolithotomy surgery.
Exclusion criteria
Exclusion criteria: Patients with sensitivity to probiotics Patients with severe immunodeficiency such as HIV Patient with contraindications for percutaneous nephrolithotomy History of receiving corticosteroids or chemotherapy Fever and active infection. CRP greater than 50 mg/L History of diabetes Having systemic inflammatory diseases Positive urine culture Kidney anomalies (such as horseshoe kidney) History of urinary stone surgeries Using Double J
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This study was designed to investigate the effect of probiotics on reducing systemic inflammatory response syndrome (SIRS) and postoperative complications of percutaneous nephrolithotomy (PCNL). Timepoint: Blood and urine tests, SIRS criteria according to the relevant questionnaire, will be checked 24 hours before and after the operation. Patient follow-up, including length of stay, rate of postoperative infections, urinary and systemic infections after surgery, incidence of serious complications (Clavin-Dindo), incidence of serious complications after surgery, including sepsis and bleeding, will be followed for 12 weeks after the operation. Method of measurement: Medical diagnostic laboratory and questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Zahra Navi
Tehran University of Medical Sciences
Outcome results
None listed